Cp*Co(III)-Catalyzed C−H Hydroarylation of Alkynes and Alkenes and Beyond: A Versatile Synthetic Tool

The use of earth-abundant first-row transition metals, such as cobalt, in C−H activation reactions for the construction and functionalization of a wide variety of structures has become a central topic in synthetic chemistry over the last few years. In this context, the emergence of cobalt catalysts...

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Detalles Bibliográficos
Autores: Carral Menoyo, Asier, Sotomayor Anduiza, María Nuria, Lete Expósito, María Esther
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/64179
Acceso en línea:http://hdl.handle.net/10810/64179
Access Level:acceso abierto
Palabra clave:cobalt
C-H activation
hydroarylation
alkene
alkyne
metal catalysis
Descripción
Sumario:The use of earth-abundant first-row transition metals, such as cobalt, in C−H activation reactions for the construction and functionalization of a wide variety of structures has become a central topic in synthetic chemistry over the last few years. In this context, the emergence of cobalt catalysts bearing pentamethylcyclopentadienyl ligands (Cp*) has had a major impact on the development of synthetic methodologies. Cp*Co- (III) complexes have been proven to possess unique reactivity compared, for example, to their Rh(III) counterparts, obtaining improved chemo- or regioselectivities, as well as yielding new reactivities. This perspective is focused on recent advances on the alkylation and alkenylation reactions of (hetero)arenes with alkenes and alkynes under Cp*Co(III) catalysis.