Design of polymeric and hybrid nanostructures for drug delivery and theranostic applications

Nanomedicine attempts to solve some of the main limitations of materials and techniques currently used in clinical practice. To do that, the design and fabrication of the so-called nanoplatforms has been envisaged. These allow the encapsulation, protection and delivery of bioactive molecules but als...

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Detalles Bibliográficos
Autor: Villar Álvarez, Eva María
Tipo de recurso: tesis doctoral
Fecha de publicación:2018
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/17466
Acceso en línea:http://hdl.handle.net/10347/17466
Access Level:acceso abierto
Palabra clave:Materias::Investigación::22 Física::2206 Física molecular::220610 Polímeros
Materias::Investigación::33 Ciencias tecnológicas::3312 Tecnología de materiales::331208 Propiedades de los materiales
Descripción
Sumario:Nanomedicine attempts to solve some of the main limitations of materials and techniques currently used in clinical practice. To do that, the design and fabrication of the so-called nanoplatforms has been envisaged. These allow the encapsulation, protection and delivery of bioactive molecules but also provide new functionalities thanks to their exceptional properties. This work is focused on the design of biocompatible polymeric nanoparticles to enable the administration of different drugs, single or in combination, for the treatment of common diseases as diabetes, infections or tumors. In addition, several multifunctional hybrid nanoplatforms have been designed for cancer theranostics and combinatorial therapeutics.