Histology of geographic atrophy secondary to age-related macular degeneration. A Multilayer Approach

The aim is to systematically characterize histologic features of multiple chorioretinal layers in eyes with geographic atrophy, or complete retinal pigment epithelium (RPE) and outer retinal atrophy, secondary to age-related macular degeneration, including Henle fiber layer and outer nuclear layer;...

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Detalles Bibliográficos
Autores: Li, Miaoling, Huisingh, Carrie, Messinger, Jeffrey, Dolz Marco, Rosa, Ferrara, Daniela, Freund, K. Bailey, Curcio, Christine A.
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universidad Católica de Valencia San Vicente Mártir
Repositorio:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
Idioma:inglés
OAI Identifier:oai:riucv.ucv.es:20.500.12466/6796
Acceso en línea:https://hdl.handle.net/20.500.12466/6796
Access Level:acceso abierto
Palabra clave:Photoreceptors
Retina
Müller cells
Retinal pigment epithelium
Choriocapillaris
Bruch membrane
Geographic atrophy
Histology
Morphometry
32 Ciencias Médicas
3201.09 Oftalmología
Descripción
Sumario:The aim is to systematically characterize histologic features of multiple chorioretinal layers in eyes with geographic atrophy, or complete retinal pigment epithelium (RPE) and outer retinal atrophy, secondary to age-related macular degeneration, including Henle fiber layer and outer nuclear layer; and to compare these changes to those in the underlying RPE-Bruch membrane—choriocapillaris complex and associated extracellular deposits.