High-Resolution Mapping of Chromatin Conformation in Cardiac Myocytes Reveals Structural Remodeling of the Epigenome in Heart Failure

[Background] Cardiovascular disease is associated with epigenomic changes in the heart; however, the endogenous structure of cardiac myocyte chromatin has never been determined.

Detalhes bibliográficos
Autores: Rosa-Garrido, Manuel, Chapski, Douglas J., Schmitt, Anthony D., Kimball, Todd H., Karbassi, Elaheh, Monte, Emma, Balderas, Enrique, Pellegrini, Matteo, Shih, Tsai-Ting, Soehalim, Elizabeth, Liem, David, Ping, Peipei, Galjart, Niels J., Ren, Shuxun, Wang, Yibin, Ren, Bing, Vondriska, Thomas M.
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/414522
Acesso em linha:http://hdl.handle.net/10261/414522
https://api.elsevier.com/content/abstract/scopus_id/85032149322
Access Level:acceso abierto
Palavra-chave:Epigenomics
Genomics
Heart failure
Hypertrophy
Descrição
Resumo:[Background] Cardiovascular disease is associated with epigenomic changes in the heart; however, the endogenous structure of cardiac myocyte chromatin has never been determined.

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