Fluorinated carbohydrates as chemical probes formolecular recognition studies. Current statusand perspectives
This review provides an extensive summary of the effects of carbohydrate fluorination with regard to changes in physical, chemical and biological properties with respect to regular saccharides. The specific structural, conformational, stability, reactivity and interaction features of fluorinated sug...
| Autores: | , , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2020 |
| País: | España |
| Institución: | Universidad del País Vasco |
| Repositorio: | Addi. Archivo Digital para la Docencia y la Investigación |
| OAI Identifier: | oai:addi.ehu.eus:10810/46950 |
| Acceso en línea: | http://hdl.handle.net/10810/46950 |
| Access Level: | acceso abierto |
| Palabra clave: | nuclear-magnetic-resonance udp-galactopyranose mutase mechanism-based inhibitors hydrogen-bond acidity chemoenzymatic synthesis enantioselective synthesis organic fluorine conformational behavior aromatic interactions metabolic-inhibitors |
| Sumario: | This review provides an extensive summary of the effects of carbohydrate fluorination with regard to changes in physical, chemical and biological properties with respect to regular saccharides. The specific structural, conformational, stability, reactivity and interaction features of fluorinated sugars are described, as well as their applications as probes and in chemical biology. |
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