Calcium binding and voltage gating in cx46 hemichannels

The opening of connexin (Cx) hemichannels in the membrane is tightly regulated by calcium (Ca2+) and membrane voltage. Electrophysiological and atomic force microscopy experiments indicate that Ca2+ stabilizes the hemichannel closed state. However, struct

Detalles Bibliográficos
Autores: Pinto, Bernardo I, Pupo, Amaury, Garcia, Isaac E, Mena-Ulecia, Karel, Martinez, Agustin D, Latorre, Ramon, Gonzalez, Carlos
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Chile
Idioma:inglés
OAI Identifier:oai:repositorio.anid.cl:10533/231962
Acceso en línea:https://hdl.handle.net/10533/231962
Access Level:acceso abierto
Descripción
Sumario:The opening of connexin (Cx) hemichannels in the membrane is tightly regulated by calcium (Ca2+) and membrane voltage. Electrophysiological and atomic force microscopy experiments indicate that Ca2+ stabilizes the hemichannel closed state. However, struct