Is the recent increment in attributable deaths to type- 2 diabetes (T2D) associated with the latest chikungunya outbreak in a major epidemic area in Brazil?

Introduction: Chikungunya virus (CHIKV) can negatively influence outcomes in patients with pre-existing conditions. We investigated the association between the recent CHIKV outbreak and increased type 2 diabetes (T2D)-attributable deaths. Methods: Monthly averages of T2D-attributable deaths between...

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Detalhes bibliográficos
Autores: Cavalcanti, Luciano Pamplona de Góes, D’angelo, Sara Mendes, Lemos, Daniele Rocha Queiroz, Barreto, Francisca Kalline de Almeida, Siqueira, André Machado, Miyajima, Fabio
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:Brasil
Recursos:Universidade Federal do Ceará (UFC)
Repositorio:Repositório Institucional da Universidade Federal do Ceará (UFC)
Idioma:inglés
OAI Identifier:oai:repositorio.ufc.br:riufc/32253
Acesso em linha:http://www.repositorio.ufc.br/handle/riufc/32253
Access Level:acceso abierto
Palavra-chave:Vírus Chikungunya
Chikungunya virus
Arbovirus
Arboviruses
Diabetes Mellitus
Descrição
Resumo:Introduction: Chikungunya virus (CHIKV) can negatively influence outcomes in patients with pre-existing conditions. We investigated the association between the recent CHIKV outbreak and increased type 2 diabetes (T2D)-attributable deaths. Methods: Monthly averages of T2D-attributable deaths between 2001 and 2016 were determined and compared to the equivalent data for 2017 and the recent CHIKV outbreak. Results: CHKV outbreak peaked in April 2017 with 4,394.4 cases/100,000 inhabitants, while T2D-attributable deaths in the same period increased by 35.2%. Conclusions: T2D-attributable deaths significantly increased compared to the previous data, which overlapped with CHIKV incidence. The pathophysiology of this association warrants further investigations.