Intranasal Liposomal Formulation of Spike Protein Adjuvanted with CpG Protects and Boosts Heterologous Immunity of hACE2 Transgenic Mice to SARS-CoV-2 Infection

We would like to thank the great support received from Christoph Milewski, Wanise Barroso, Isabel M. A. Freire, and Fabienne P. de Paiva from ICTB, Fiocruz. Also thank João Calixto and his team from CIEnP; Carsten Wrenger and his team from ICB-USP; Felipe Rodrigues da Silva and Carlos Eduardo de And...

Full description

Bibliographic Details
Authors: Russo, Momtchilo, Mendes-Corrê, Maria Cássia, Lins, Bruna B., Kersten, Victor, Pernambuco Filho, Paulo C. A., Martins, Toni Ricardo, Tozetto-Mendoza, Tânia Regina, Vilas Boas, Lucy Santos, Gomes, Brisa Moreira, Dati, Livia Mendonça Munhoz, Duarte-Neto, Amaro Nunes, Reigado, Gustavo Roncoli, Frederico, Ana Beatriz T., Cunha, Danielle R. de A. de Brito e, Paula, Anderson Vicente de, Silva, José Igor G. da, Vasconcelos, Carlos F. Moreira, Chambergo, Felipe S., Nunes, Viviane Abreu, Ano Bom, Ana Paula Dinis, Castilho, Leda R., Martins, Rodrigo A. P., Hirata, Mario Hiroyuki, Mirotti, Luciana
Format: article
Status:Published version
Publication Date:2023
Country:Brasil
Institution:Fundação Oswaldo Cruz (FIOCRUZ)
Repository:Repositório Institucional da FIOCRUZ (ARCA)
Language:English
OAI Identifier:oai:arca.fiocruz.br:icict/61605
Online Access:https://arca.fiocruz.br/handle/icict/61605
Access Level:Open access
Keyword:CpG-ODNs
SARS-CoV-2
Cationic Liposome
hACE2 Transgenic Mice
Heterologous Immunity
Intranasal Route
Spike Protein
Vaccine
03 Saúde e Bem-Estar
Description
Summary:We would like to thank the great support received from Christoph Milewski, Wanise Barroso, Isabel M. A. Freire, and Fabienne P. de Paiva from ICTB, Fiocruz. Also thank João Calixto and his team from CIEnP; Carsten Wrenger and his team from ICB-USP; Felipe Rodrigues da Silva and Carlos Eduardo de Andrade Lima da Rocha from Plataforma Internacional de Ciência, Tecnologia e Inovação em Saúde (PICTIS), Fiocruz; and Jessica Santana, INOVA/Fiocruz scholarship holder.

Similar Items