Quimioterapia Adjuvante no Câncer da Mama

A retrospectiva analysis of adjuvant chemotherapy in 95 patients with breast cancer was carried out. Patient stratification was made according to pathological status of axilary lymphonodes: group A patients with 1-3 positive nodes and group B patients with more than 3 positive lymphnodes. At sixty m...

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Detalhes bibliográficos
Autores: Broecker Neto, Adalberto, Lago, Sérgio, Radke, Rodolfo Coutinho, Costa, Ailzo José da, Hudson, Iara A.
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:Brasil
Recursos:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
Repositorio:Revista Brasileira de Cancerologia (Online)
Idioma:portugués
OAI Identifier:oai:rbc.inca.gov.br:article/3320
Acesso em linha:https://rbc.inca.gov.br/index.php/revista/article/view/3320
Access Level:acceso abierto
Palavra-chave:Câncer da Mama
Quimioterapia Adjuvante
Breast Cancer
Adjuvant Chemotherapy
Descrição
Resumo:A retrospectiva analysis of adjuvant chemotherapy in 95 patients with breast cancer was carried out. Patient stratification was made according to pathological status of axilary lymphonodes: group A patients with 1-3 positive nodes and group B patients with more than 3 positive lymphnodes. At sixty months the probability of survival was 86.1% for group A and 83% for group B (p=0.042) and, probability of disease free survival was 86.1%> in group A and 64.4% in group B (p<0.001). Forty nine patients were foilowed for at least 2 years and analysis after 24 months showed survival of 95.4% for group A and 85,1% for B (p=0.014) and, survival free of disease of 86.3% in group A and 66,6% in group B (p =0.415). Recurrence rate was 23.4% for patients receiving 85%> or more of programmed dose and 45% for patients whith lower doses. Local recurrences were identical for patients with or without radiotherapy. A comparison with the Milan study was made.