Si-tricalcium phosphate cement: preparation, characterization and bioactivity in SBF

There are evidences considering the effectiveness of Si on enhancing biological properties of calcium phosphates; however, there are not many works relating to the Si-alpha-TCP bone cement. The influence of silicon doping on the properties of Α-TCP cement was analyzed. Si-TCP was obtained by a solid...

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Detalhes bibliográficos
Autores: Motisuke, Mariana [UNIFESP], Carrodeguas, Raúl García, Zavaglia, Cecília Amélia De Carvalho
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:Brasil
Recursos:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:inglés
OAI Identifier:oai:repositorio.unifesp.br:11600/6752
Acesso em linha:http://dx.doi.org/10.1590/S1516-14392011005000065
http://repositorio.unifesp.br/handle/11600/6752
Access Level:acceso abierto
Palavra-chave:calcium phosphate cements
tricalcium phosphate
wollastonite
silicon-doped tricalcium phosphate
biomedical application
Descrição
Resumo:There are evidences considering the effectiveness of Si on enhancing biological properties of calcium phosphates; however, there are not many works relating to the Si-alpha-TCP bone cement. The influence of silicon doping on the properties of Α-TCP cement was analyzed. Si-TCP was obtained by a solid state reaction employing CaCO3, CaHPO4 and CaSiO3 and powder was analyzed by XRD, FTIR, XRF and BET specific area. Cement samples were analyzed for their surface of fracture morphology, mechanical resistance and SBF bioactivity. Cement mechanical resistance was not satisfactory for biomedical application; nonetheless, sample's surface was coated by an apatite layer after immersion in SBF. Notwithstanding, to ensure that silicon is the element responsible for increasing the material's bioactivity it is necessary to evaluate the in vivo performance of the bone cement obtained in this work.