Evidence on Mortality in Liver Transplantation Candidates: Integrative Literature Review

The objective of this paper was to analyze the evidence available in the literature about mortality and its risk factors in liver transplantation candidates. An integrative literature review was carried out, based on the following steps: elaboration of the research question, search in the literature...

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Bibliographic Details
Authors: Emanuelly Marinho Moreno, Stephani, Maia Marques, Daniella, Piccoli Prochnon, Nathalia, Maria Galvão, Cristina, Dal Sasso Mendes, Karina
Format: article
Status:Published version
Publication Date:2022
Country:Brasil
Institution:Associação Brasileira de Transplante de Órgãos (ABTO)
Repository:Brazilian Journal of Transplantation
Language:English
Portuguese
Spanish
OAI Identifier:oai:ojs3.emnuvens.com.br:article/440
Online Access:https://bjt.emnuvens.com.br/revista/article/view/440
Access Level:Open access
Keyword:Transplante de Fígado
Mortalidade
Listas de Espera
Fatores de Risco
Liver Transplantatiom
Mortality
Waiting Lists
Risk Factors
Transplante de Hígado
Mortalidad
Factores de Riesgo
Description
Summary:The objective of this paper was to analyze the evidence available in the literature about mortality and its risk factors in liver transplantation candidates. An integrative literature review was carried out, based on the following steps: elaboration of the research question, search in the literature of primary studies, data extraction, studies evaluation, analysis and synthesis of the results, and review presentation. The Latin American and Caribbean Health Sciences Literature (LILACS), National Library of Medicine and the National Institutes of Health (PubMed), and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases were accessed for the search. Primary studies that portrayed the liver transplantation candidates’ mortality, published in English, Portuguese, and Spanish, over the last five years were included. Among the eight studies analyzed, it was observed that the risk factors associated with mortality and identified in more than one study were: encephalopathy (n=3; 37.5%), model for end-stage liver disease (MELD) (n=3; 37.5%), frailty (n=3; 37.5%), body mass index (n=2; 25%), hepatocellular carcinoma (n=2; 25%), sex (women) (n=2; 25%), and ascites (n=2; 25%). It is expected that the synthesis of evidence supports the planning of the intervention aimed at prioritizing care for patients at higher risk of death, contributing to the quality of health care in liver transplantation.