Influence of temperature, anions and size distribution on the zeta potential of DMPC, DPPC and DMPE lipid vesicles

The purpose of the work is to compare the influence of the multilamellarity, phase state, lipid head groups and ionic media on the origin of the surface potential of lipid membranes. With this aim, we present a new analysis of the zeta potential of multilamellar and unilamellar vesicles composed by...

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Detalles Bibliográficos
Autores: Morini, Marcela Ana, Sierra, Maria Belen, Pedroni, Viviana Isabel, Alarcon, Laureano Martin, Appignanesi, Gustavo Adrian, Disalvo, Edgardo Anibal
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/4715
Acceso en línea:http://hdl.handle.net/11336/4715
Access Level:acceso abierto
Palabra clave:Phospholipids
Multilamelar
Vesicles
Unilamellar Vesicles
Zeta Potential
Surface Charge-Anions-Water
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:The purpose of the work is to compare the influence of the multilamellarity, phase state, lipid head groups and ionic media on the origin of the surface potential of lipid membranes. With this aim, we present a new analysis of the zeta potential of multilamellar and unilamellar vesicles composed by phosphatidylcholines (PC) and phosphatidylethanolamines (PE) dispersed in water and ionic solutions of polarizable anions, at temperatures below and above the phase transition. In general, the adsorption of anions seems to explain the origin of the zeta potential in vesicles only above the transition temperature (Tc). In this case, the sign of the surface potential is ascribed to a partial orientation of head group moiety towards the aqueous phase. This is noticeable in PC head groups but not in PEs, due to the strong lateral interaction between PO and NH group in PE.